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[Reversible multifocal encephalopathy in fulminant eclampsia].

H Köller1, T Somville, A Aulich

  • 1Neurologische Klinik der Heinrich-Heine-Universität Düsseldorf, Postfach 101007, 40001 Düsseldorf. koeller@neurologie.uni-duesseldorf.de

Der Nervenarzt
|April 26, 2001
PubMed
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Fulminant eclampsia, a rare pregnancy complication, can cause severe brain swelling with neurological symptoms. Prompt treatment including pregnancy termination can lead to full recovery.

Area of Science:

  • Neurology
  • Obstetrics
  • Radiology

Background:

  • Fulminant eclampsia is a rare, severe form of pregnancy-induced hypertension.
  • It presents with neurological deficits and convulsions, often in the third trimester.

Observation:

  • Eight women aged 22-35 with fulminant eclampsia presented with seizures and central paresis.
  • Neuroimaging revealed multifocal lesions in grey and white matter, predominantly in occipital lobes.
  • Transcranial Doppler sonography indicated increased cerebral blood flow velocities.

Findings:

  • Fulminant eclampsia can induce a severe, multifocal encephalopathy.
  • The condition affects both grey and white matter, with a predilection for occipital lobes.
  • Increased cerebral blood flow velocities were observed.

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Implications:

  • Early diagnosis and intervention are crucial for managing fulminant eclampsia.
  • Prompt treatment, including antihypertensive and anticonvulsive medications, is vital.
  • Operative termination of pregnancy, combined with medical management, can lead to reversible neurological deficits.