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Allogeneic transplantation of blood stem cells: coming of age?

P Dreger1, N Schmitz

  • 1Second Department of Medicine, University of Kiel, Chemnitzstrasse 33, 24116 Kiel, Germany. p.dreger@med2.uni-kiel.de

Annals of Hematology
|April 26, 2001
PubMed

Mobilized peripheral blood progenitor cells (PBSC) are increasingly being used instead of bone marrow for allogeneic transplantation. The purpose of the present article is to give a concise and clinically oriented overview on current results and perspectives of allogeneic peripheral blood stem cell transplantation, with particular focus on reconstitution of hematopoiesis and the immune system, graft-versus-host disease, graft-versus-leukemia effects, intensity-reduced conditioning, and graft engineering.

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