Related Experiment Video
Updated: Aug 19, 2026

Non-invasive Optical Imaging of the Lymphatic Vasculature of a Mouse
Published on: March 8, 2013
Effects of leg rotation on lymph flow and pressure in rabbit lumbar lymph circulation: in vivo experiments and
1The 1st Department of Physiology, Shinshu University School of Medicine, Matsumoto, Japan. fikomi@sch.md.shinshu-u.ac.jp
Abstract:
The intraluminal lymphatic pressure in rabbit lumbar lymphatic trunks was determined. To estimate the lymphatic pressure, graphical analysis was performed from lymph outflow pressure-flow rate relationship and lymph infusion pressure-flow rate relationship. A direct measurement technique with a T-tube was also carried out to measure the pressure in the lumbar lymphatic. The rabbit leg was passively rotated at 0.3 Hz in the diameter of 8 cm to enhance the lymphatic pump activity of the leg. The estimated pressure and measured pressure in the lymphatics were 6.50 and 7.14 +/- 2.38 cmH2O, respectively. It was confirmed that similar values could be obtained from these two methods. The lymphatic pumping in the leg may affect a distribution of pressure in the lumbar lymphatic system.

