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SRY-negative XX sex reversal in a pony: a case report
L Vaughan1, W Schofield, S Ennis
1Faculty of Veterinary Medicine, University College Dublin, Ballsbridge, Ireland.
Theriogenology
|April 27, 2001
Abstract:
A three year old pony with sexually ambiguous external genitalia was found to have a normal female karyotype (64, XX) and bilateral inguinal testes. The PCR analysis of blood samples revealed the absence of the Y chromosome sequences SRY, eTSPY and ZFY. No Y chromosome sequences were identified in DNA extracted from the gonads. The mechanism whereby XX sex reversal occurs in the absence of SRY is unknown.