Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

PET/SPECT: functional imaging beyond flow.

A A Lammertsma1

  • 1PET Centre, University Hospital, Vrije Universiteit, PO Box 7057, 1022 MB, Amsterdam, The Netherlands. aa.lammertsma@azvu.nl

Vision Research
|April 27, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Caloric restriction reduces proteinuria in male rats with established nephropathy.

Physiological reports·2024
Same author

A generic curriculum development model for the biomedical physics component of the educational and training programmes of the non-physics healthcare professions.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)·2021
Same author

Harmonisation of PET/CT contrast recovery performance for brain studies.

European journal of nuclear medicine and molecular imaging·2021
Same author

Quantification of [<sup>18</sup>F]afatinib using PET/CT in NSCLC patients: a feasibility study.

EJNMMI research·2020
Same author

Imaging disease activity of rheumatoid arthritis by macrophage targeting using second generation translocator protein positron emission tomography tracers.

PloS one·2019
Same author

Automated SPECT analysis compared with expert visual scoring for the detection of FFR-defined coronary artery disease.

European journal of nuclear medicine and molecular imaging·2018
Same journal

Computational and mathematical models in vision: Quantitative approaches to understanding visual perception.

Vision research·2026
Same journal

Complex interactions between lightness, chroma, and hue in color ensemble perception.

Vision research·2026
Same journal

Driving with autism spectrum disorder: Exploring the impact of tactile hazard warnings on gaze behavior and hazard responses.

Vision research·2026
Same journal

Early visual processing in adults with ADHD: evidence from contrast sensitivity, spatial integration, and external noise.

Vision research·2026
Same journal

Pupil reflexes generate the peripheral drift illusion due to ON/OFF motion responses.

Vision research·2026
Same journal

Perceived direction of glass patterns can flip by 90°: A neural model.

Vision research·2026
See all related articles

Positron emission tomography (PET) and single photon emission tomography (SPECT) offer insights into regional tissue function. Future neuroactivation studies using these techniques will likely involve advanced ligand-based approaches.

Area of Science:

  • Medical Imaging
  • Nuclear Medicine
  • Neuroscience

Background:

  • Positron Emission Tomography (PET) and Single Photon Emission Tomography (SPECT) are crucial nuclear imaging techniques.
  • Understanding their principles, strengths, and weaknesses is essential for effective application.
  • Both modalities allow for the imaging and measurement of regional tissue function, determined by the specific radiotracer used.

Purpose of the Study:

  • To review the fundamental principles of PET and SPECT imaging.
  • To discuss the comparative advantages and limitations of PET and SPECT.
  • To explore the application of PET in neuroactivation studies and propose future directions.

Main Methods:

  • Review of established principles and literature on PET and SPECT.

Related Experiment Videos

  • Analysis of existing neuroactivation studies utilizing perfusion and metabolism tracers.
  • Discussion of potential methodologies for ligand-based activation studies.

    • Main Results:

    • PET and SPECT enable visualization and quantification of regional tissue function.
    • PET is particularly adept at measuring functional parameters.
    • Neuroactivation studies can be effectively conducted using perfusion and metabolism tracers with PET.

    Conclusions:

    • Ligand-based approaches represent a promising future for PET and SPECT neuroactivation studies.
    • Further research into ligand activation methodologies is warranted.
    • PET and SPECT remain valuable tools for investigating brain function.