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Related Concept Videos

Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term proteomics...
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
Positron Emission Tomography01:29

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
Brain Imaging01:14

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).

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Related Experiment Video

Updated: Jun 21, 2026

Molecular Imaging to Target Transplanted Muscle Progenitor Cells
09:24

Molecular Imaging to Target Transplanted Muscle Progenitor Cells

Published on: March 27, 2013

Molecular imaging.

R Weissleder1, U Mahmood

  • 1Center for Molecular Imaging Research, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Bldg 149, Rm 5403, Charlestown, MA 02129, USA. weissler\der@helix.mgh.harvard.edu

Radiology
|April 27, 2001
PubMed
Summary
This summary is machine-generated.

Molecular imaging enables in vivo study of biologic processes at the cellular level. This approach targets molecular abnormalities for earlier disease detection and treatment assessment.

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Area of Science:

  • Biomedical imaging
  • Molecular biology
  • Radiology

Background:

  • Molecular imaging involves in vivo characterization of biologic processes at the cellular and molecular level.
  • It differs from classical diagnostic imaging by probing molecular abnormalities underlying disease, not just end effects.
  • Radiology research efforts align with developing novel agents, signal amplification, and imaging technologies for molecular imaging.

Purpose of the Study:

  • To present recent developments in molecular sciences and medicine.
  • To demonstrate the experimental use of imaging for assessing specific molecular targets.
  • To highlight the potential of molecular imaging in future medical applications.

Main Methods:

  • Review of recent advancements in molecular sciences and medicine.
  • Experimental application of imaging techniques to assess molecular targets in vivo.
  • Discussion of novel agents, signal amplification strategies, and imaging technologies.

Main Results:

  • Molecular imaging allows for the in vivo characterization of biologic processes at the cellular and molecular level.
  • Experimental imaging successfully assessed specific molecular targets.
  • The field is rapidly developing with contributions from radiology research.

Conclusions:

  • Molecular imaging offers a new paradigm for understanding and diagnosing diseases.
  • Future applications include earlier disease detection, characterization, and molecular assessment of treatment efficacy.
  • Radiologists are poised to lead the development and implementation of this burgeoning field.