Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Microscopic polyangiitis complicated with massive intestinal bleeding.

S Ueda1, M Matsumoto, T Ahn

  • 1Department of Internal Medicine, Nara Prefectural Gojo Hospital, Japan.

Journal of Gastroenterology
|April 28, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Expression of heregulin alpha, erbB2, and erbB3 and their influences on proliferation of gastric epithelial cells.

Gastroenterology·1999
Same author

KDR/Flk-1 is a major regulator of vascular endothelial growth factor-induced tumor development and angiogenesis in murine hepatocellular carcinoma cells.

Hepatology (Baltimore, Md.)·1999
Same author

Detection of anaphylactic reaction in the percutaneously sensitized mouse using the AW method.

Biological & pharmaceutical bulletin·1999
Same author

Glycyrrhizin inhibits TNF-induced, but not Fas-mediated, apoptosis in the human hepatoblastoma line HepG2.

Biological & pharmaceutical bulletin·1999
Same author

Bileaflet mechanical valve (St. Jude Medical valve) replacement in long-term dialysis patients.

The Annals of thoracic surgery·1999
Same author

Cancer gene therapy with HSV-tk/GCV system depends on T-cell-mediated immune responses and causes apoptotic death of tumor cells in vivo.

International journal of cancer·1999

Microscopic polyangiitis (MPA) can cause rare but severe intestinal bleeding. This case highlights MPA

Area of Science:

  • Rheumatology and Nephrology
  • Gastroenterology and Pulmonology

Background:

  • Microscopic polyangiitis (MPA) commonly affects the kidneys and lungs.
  • Gastrointestinal bleeding is an infrequent complication of MPA.

Observation:

  • A 74-year-old male presented with fever, leucocytosis, and renal dysfunction.
  • He developed massive melena, diagnosed as small intestinal arterial bleeding via angiography.
  • The patient experienced pulmonary hemorrhage post-embolization and later succumbed to recurrent bleeding.

Findings:

  • This case illustrates a rare presentation of MPA with massive small intestinal arterial bleeding.
  • MPA was associated with severe renal dysfunction, gastrointestinal hemorrhage, and pulmonary hemorrhage.
  • Transarterial embolization (TAE) achieved initial hemostasis for intestinal bleeding.

Related Experiment Videos

Implications:

  • Gastrointestinal arterial bleeding should be considered a serious, albeit rare, complication in MPA patients.
  • Early recognition and management of MPA-related gastrointestinal bleeding are crucial.
  • Combined immunosuppressive therapy (corticosteroids and cyclophosphamide) showed efficacy but did not prevent fatal recurrence.