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Predictive value of human chorionic gonadotrophin beta-hCG in early pregnancy after assisted conception
F Zayed1, I Ghazawi, L Francis
1Jordan University of Science and Technology, Amman. fhmzayed@just.edu.jo
Objective:
This study was designed to evaluate the predictive value of beta-hCG levels in predicting the pregnancy outcome.
Methods:
A retrospective analysis was done on 423 pregnant patients following assisted conception (stimulated in vitro fertilization [SIVF] and stimulated intra uterine insemination [SIUI]). These were monitored with plasma beta-hCG on day +18 post hCG injection. Ongoing pregnancy was defined as greater than 20 weeks.
Results:
Four hundred twenty three patients had a positive serum quantitative beta-hCG level 18 days post hCG injection. Of these 321 (75.9%) were ongoing pregnancies. The spontaneous miscarriages were 98 (23.2%), and four ectopic pregnancies were recorded. Of the successful pregnancies, 279 were single births, and 42 were multiple births (15.1%), that is either twins (31) or triplets (11). Tables were calculated to help predicting the pregnancy outcome.
Conclusions:
It can be shown that +18 levels of beta-hCG in cases of assisted conception are useful and provide predictive information concerning pregnancy outcome which should be helpful for the staff and the infertility patients.