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Novel non-peptide ligands for the somatostatin sst3 receptor
C Moinet1, M O Contour-Galcéra, L Poitout
1Institut Henri Beaufour, Les Ulis, France. christophe.moinet@beaufour-ipsen.com
Bioorganic & Medicinal Chemistry Letters
|May 1, 2001
Abstract:
A series of imidazole derivatives has been prepared using high throughput parallel synthesis. Several compounds showed high affinity (Ki in 10(-6)-10(-8) M range) and selectivity at recombinant human somatostatin receptor subtype 3 (hsst3).