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Hypoadrenocorticism in a cat.

J Stonehewer1, S Tasker

  • 1Department of Veterinary Clinical Science and Animal Husbandry, University of Liverpool, Small Animal Hospital, Merseyside.

The Journal of Small Animal Practice
|May 1, 2001
PubMed
Summary
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This study reports a case of primary hypoadrenocorticism in a cat presenting with dysphagia. Prompt diagnosis and treatment with fludrocortisone acetate led to a full recovery and long-term survival.

Area of Science:

  • Veterinary Medicine
  • Endocrinology
  • Internal Medicine

Background:

  • Primary hypoadrenocorticism, a rare endocrine disorder, involves insufficient production of adrenal hormones.
  • Clinical signs can be vague and intermittent, making diagnosis challenging.

Observation:

  • An eight-year-old neutered male cat presented with dysphagia, lethargy, weight loss, and gastrointestinal signs.
  • Physical examination revealed dehydration and poor body condition.
  • Laboratory findings included anemia, electrolyte imbalances (hyperkalemia, hyponatremia, hypochloraemia), and elevated creatinine and creatine kinase.

Findings:

  • Adrenocorticotropic hormone (ACTH) stimulation testing and endogenous plasma ACTH levels confirmed primary adrenocortical insufficiency.
  • Initial treatment involved fluid therapy, dexamethasone, and oral fludrocortisone acetate.

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Implications:

  • Early diagnosis and appropriate treatment, particularly with fludrocortisone acetate, can lead to successful outcomes in feline hypoadrenocorticism.
  • This case highlights the importance of considering hypoadrenocorticism in cats with non-specific clinical signs.