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Related Experiment Videos

Neurorehabilitation: a bridge between basic science and clinical practice.

J Kesselring1

  • 1Department of Neurology, Rehabilitation Centre, CH-7317 Valens, Switzerland. kesselring.klival@spin.ch

European Journal of Neurology
|May 1, 2001
PubMed
Summary

Neurology is shifting from viewing the central nervous system as irreparable to recognizing its plasticity. Therapeutic exercises actively support and enhance the brain

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Area of Science:

  • Neurology
  • Neuroscience
  • Rehabilitation Science

Background:

  • Historically, central nervous system (CNS) damage was considered irreparable, with nerve paths fixed in the adult brain.
  • This dogma, exemplified by Cajal (1928), suggested no regeneration was possible after development.
  • However, early insights by Foerster (1936) highlighted the organism's inherent capacity for compensation and adaptation following neurological injury.

Purpose of the Study:

  • To challenge the historical dogma of CNS irreparability.
  • To emphasize the neuroplasticity and adaptability of the adult brain.
  • To underscore the crucial role of therapeutic exercises in neurological recovery.

Main Methods:

  • Historical analysis of neurological perspectives on CNS repair.

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  • Review of foundational texts on neuroplasticity and rehabilitation.
  • Interpretation of early 20th-century neurological literature regarding brain function and recovery.

    • Main Results:

    • The study revisits and validates early observations on the brain's remarkable plasticity and adaptability.
    • It demonstrates that neurological damage does not equate to a complete loss of function or potential for recovery.
    • Foerster's work is presented as prescient, anticipating modern understanding of spontaneous neurological restoration.

    Conclusions:

    • A paradigm shift is occurring in neurology, moving beyond the concept of incurable CNS damage.
    • The adult brain exhibits significant plasticity, allowing for spontaneous reorganization and compensation after injury.
    • Therapeutic exercises are vital for supporting, strengthening, and initiating this natural process of neurological restoration.