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Updated: Jul 26, 2026

Using an α-Bungarotoxin Binding Site Tag to Study GABA A Receptor Membrane Localization and Trafficking
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Published on: March 28, 2014

GABA uptake by rabbit restiform body homogenates

H Hydèn1, A Cupello, M V Rapallino

  • 1Institute of Neurobiology, University of Goteborg, Sweden.

The International Journal of Neuroscience
|May 1, 2001
PubMed

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Rab proteins constitute the largest family of monomeric GTPases, of which 70 members are present in humans. Rab proteins and their effectors regulate consecutive stages of vesicle transport such as vesicle transport, docking, and fusion to the correct recipient membrane.
Rab proteins switch between a cytosolic, GDP-bound inactive state and a membrane-anchored, GTP-bound active state. By themselves, Rabs show slow rates of GDP/GTP exchange and GTP hydrolysis. Thus, Rab proteins are considered...