Related Experiment Video
Updated: Oct 7, 2026

Robotic Myotomy and Partial Fundoplication for Achalasia
Published on: August 11, 2023
Esophagogastric dissociation versus fundoplication: Which is best for severely neurologically impaired children?
C Gatti1, G F di Abriola, M Villa
1Digestive Surgery Unit, Bambino Gesù Children's Hospital, Roma, Italy.
Insights
Esophagogastric dissociation (EGD) in neurologically impaired children (NIC) led to better nutritional outcomes and fewer respiratory infections compared to fundoplication and gastrostomy. EGD is a viable primary surgical option for these complex patients.
Area of Science:
- Pediatric surgery
- Gastroenterology
- Nutritional rehabilitation
Background:
- Neurologically impaired children (NIC) frequently experience feeding difficulties, reflux, and respiratory issues.
- Traditional treatments like fundoplication and gastrostomy have limitations.
- Esophagogastric dissociation (EGD) emerged as a potential alternative.
Purpose of the Study:
- To compare the efficacy of EGD versus fundoplication and gastrostomy in NIC.
- To evaluate nutritional status, respiratory health, and quality of life post-surgery.
Main Methods:
- Prospective study of 29 NIC refractory to medical therapy.
- Group A (n=12): fundoplication and gastrostomy. Group B (n=14): EGD.
- Analysis of anthropometric, biochemical, infection rates, hospitalization, feeding time, and quality of life pre- and post-operatively.
Main Results:
- Group B (EGD) showed significant improvements in nutritional parameters and quality of life compared to Group A.
- EGD group experienced fewer respiratory infections, shorter hospital stays, and reduced feeding times.
- Complications included bowel obstruction and anastomotic stricture in the EGD group; fundoplication group had more severe complications.
Conclusions:
- EGD demonstrates superior outcomes in nutritional rehabilitation and quality of life for NIC.
- EGD offers a significant reduction in respiratory infections and hospitalizations.
- EGD is a recommended primary surgical approach for symptomatic NIC.
Purpose:
Neurologically impaired children (NIC) often have swallowing difficulties, severe gastroesophageal reflux, recurrent respiratory infections, and malnutrition. Bianchi proposed esophagogastric dissociation (EGD) as an alternative to fundoplication and gastrostomy. The authors compared these 2 approaches.
Methods:
Twenty-nine consecutive symptomatic NIC refractory to medical therapy were enrolled in a prospective study and divided into 2 groups: A (n = 12), NIC who underwent fundoplication and gastrostomy; B (n = 14), NIC who underwent EGD. Three were excluded because of previous fundoplication. Anthropometric (percentage of the 50th percentile/age of healthy children) and biochemical parameters, respiratory infections per year, hospitalization (days per year), feeding time (minutes), and "quality of life" (parental psychological questionnaire, range 0 to 60), were analyzed (t test and Mann-Whitney test) preoperatively and 1 year postoperatively. Complications were recorded.
Results:
Compared with group A, group B presented a statistically significant increase of all anthropometric and nearly all biochemical parameters with a statistical difference in terms of respiratory infections, hospital stay, feeding time, and psychological questionnaire. In group A, 2 bowel obstructions, 1 tight fundoplication, 1 dumping syndrome, and 3 failures of fundoplication occurred. Group B presented 1 anastomotic stricture, 1 paraesophageal hernia, and 1 bowel obstruction.
Conclusions:
Compared with fundoplication and gastrostomy, EGD offered better nutritional rehabilitation, reduction in respiratory infections, and improved quality of life. EGD can be rightfully chosen as a primary procedure.
Related Concept Videos
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube through...
Peptic Ulcer Disease V: Surgical Management and Nursing Care
Surgical Interventions for Peptic Ulcer Disease
Gastroesophageal Reflux Disease II: Clinical Features and Management
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Esophageal Strictures-II: Clinical Features and Management
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Enteral Nutrition I: Orogastric and Nasogastric Feeding
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
Esophageal Perforation-II: Clinical Manifestations and Management
Clinical Manifestations:
