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A chronology of fine-scale gene mapping by linkage disequilibrium
1Biostatistics Division, Department of Health Research and Policy, Stanford University, Stanford, California 94305, USA. Lazzeroni@stanford.edu
Statistical Methods in Medical Research
|May 2, 2001
Abstract:
The past decade produced several proposals for fine-scale gene mapping using linkage disequilibrium data. The suggested methods fall into two main groups, those that rely on pairwise statistics and those that rely on haplotypes. This paper reviews each strategy's development from a chronological perspective.