Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Evolving concepts of human state dissociation.

M W Mahowald1, C H Schenck

  • 1Minnesota Regional Sleep Disorders Center, Hennepin County Medical Center, Department of Neurology, University of Minnesota Medical School, Minneapolis, MN, USA.

Archives Italiennes De Biologie
|May 2, 2001
PubMed
Summary

Basic science research, particularly in sleep function, has illuminated human state dissociation, enabling effective treatments. Continued collaboration between scientists and clinicians is vital for advancing sleep medicine.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Risk stratification for phenoconversion in patients with isolated REM sleep behavior disorder. A follow-up study from Turkey.

Revista de neurologia·2024
Same author

Cannabidiol can improve complex sleep-related behaviours associated with rapid eye movement sleep behaviour disorder in Parkinson's disease patients: a case series.

Journal of clinical pharmacy and therapeutics·2014
Same author

Rapid eye movement sleep behavior disorder: devising controlled active treatment studies for symptomatic and neuroprotective therapy--a consensus statement from the International Rapid Eye Movement Sleep Behavior Disorder Study Group.

Sleep medicine·2013
Same author

Clinicopathologic correlations in 172 cases of rapid eye movement sleep behavior disorder with or without a coexisting neurologic disorder.

Sleep medicine·2013
Same author

Prevalence and comorbidity of nocturnal wandering in the U.S. adult general population.

Neurology·2012
Same author

Pathophysiology of REM sleep behaviour disorder and relevance to neurodegenerative disease.

Brain : a journal of neurology·2007

Area of Science:

  • Neuroscience
  • Sleep Medicine
  • Basic Science Research

Background:

  • State dissociation in humans was historically misunderstood, often relegated to mystical or psychiatric explanations.
  • Advances in understanding sleep mechanisms, derived from animal research, provided crucial insights into human neurological states.

Purpose of the Study:

  • To highlight the critical role of basic science, especially sleep research, in understanding and treating human state dissociation.
  • To emphasize the importance of interdisciplinary collaboration between basic scientists and clinicians in sleep medicine.

Main Methods:

  • Application of findings from basic science animal research to the human condition.
  • Conceptualizing sleep or wakefulness as asynchronous brain activity.
  • Fostering interaction between basic scientists and clinicians.

Related Experiment Videos

Main Results:

  • Basic science research has provided effective treatment options for conditions previously considered untreatable.
  • Understanding asynchronous brain activity offers a framework for explaining state dissociation.
  • Clinical questions are guiding basic science research, creating a synergistic relationship.

Conclusions:

  • Continued basic and clinical research into state dissociation is essential for identifying and explaining more conditions.
  • Close collaboration across all scientific levels (molecular to clinical) yields significant therapeutic benefits.
  • The reciprocal relationship between basic science and clinical practice in sleep medicine is highly valuable and should be ongoing.