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QT dispersion and signal-averaged electrocardiogram in hemodialysis and CAPD patients

A Yildiz1, V Akkaya, S Sahin

  • 1Department of Internal Medicine, Istanbul School of Medicine, Turkey. alaattiny@hotmail.com

Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis
|May 2, 2001
PubMed

Insights

Patients undergoing hemodialysis (HD) and continuous ambulatory peritoneal dialysis (CAPD) show prolonged QT dispersion (QTd) and increased filtered-QRS duration compared to controls. Hemodialysis patients exhibited longer QTd, correlating with left ventricular mass index.

Area of Science:

  • Cardiology
  • Nephrology
  • Electrophysiology

Background:

  • Dialysis patients are at increased risk for arrhythmias.
  • QT dispersion (QTd) and signal-averaged electrocardiogram (SA-ECG) parameters may predict this risk.

Purpose of the Study:

  • To compare QTd and SA-ECG parameters for predicting malignant arrhythmias in hemodialysis (HD), continuous ambulatory peritoneal dialysis (CAPD), and control groups.

Main Methods:

  • Cross-sectional study comparing 28 HD, 29 CAPD, and 29 control patients.
  • Measured QTmin, QTmax, QTd, filtered QRS duration, HFLA signals, and RMS voltage.

Main Results:

  • HD and CAPD patients had increased QT parameters and filtered-QRS duration versus controls.
  • QTd was significantly prolonged in HD compared to CAPD.
  • QTd correlated with left ventricular mass index in HD patients but not CAPD patients.

Conclusions:

  • Dialysis patients exhibit prolonged QTd and increased filtered-QRS duration.
  • Hemodialysis is associated with longer QTd than CAPD.
  • Differences may relate to electrolyte variations, particularly serum Ca2+ levels.
Abstract

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