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Constrictive pericarditis associated with Marlex mesh. Two case reports.

R F Chen¹, C P Lai

¹Department of Thoracic and Cardiovascular Surgery, Taipei Medical College Hospital and Municipal Wang Fang Hospital, Taipei Medical College, School of Medicine, Republic of China.

Texas Heart Institute Journal

|May 2, 2001

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Marlex mesh used during mitral valve repair can lead to constrictive pericarditis. This pericardial substitute, intended to prevent adhesions, instead caused a fibrotic reaction and cardiac complications in two patients.

Area of Science:

Cardiovascular Surgery
Cardiac Pathology

Background:

Mitral valve repair is a common cardiac procedure.
Pericardial substitutes like Marlex mesh are sometimes used to prevent adhesions and facilitate future surgeries.

Observation:

Two patients developed constrictive pericarditis one year after mitral valve repair involving Marlex mesh.
Diagnostic imaging and cardiac catheterization confirmed constrictive pericarditis.

Findings:

Surgical exploration revealed dense, thickened fibrous tissue encasing the epicardium in both patients.
This fibrotic reaction was attributed to the presence of Marlex mesh.

Implications:

Marlex mesh, when used as a pericardial substitute, may induce a significant inflammatory and fibrotic response.

Related Experiment Videos

This reaction can lead to the development of constrictive pericarditis, potentially negating its intended benefits.