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Updated: Aug 10, 2026

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web
Published on: July 16, 2017
BioMolQuest: integrated database-based retrieval of protein structural and functional information
1Laboratory of Computational Genomics, Donald Danforth Plant Science Center, 893 N. Warson Rd, St Louis, MO 63141, USA.
Motivation:
Information about a particular protein or protein family is usually distributed among multiple databases and often in more than one entry in each database. Retrieval and organization of this information can be a laborious task. This task is complicated even further by the existence of alternative terms for the same concept.
Results:
The PDB, SWISS-PROT, ENZYME, and CATH databases have been imported into a combined relational database, BIOMOLQUEST: A powerful search engine has been built using this database as a back end. The search engine achieves significant improvements in query performance by automatically utilizing cross-references between the legacy databases. The results of the queries are presented in an organized, hierarchical way.
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