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Cell control by membrane-cytoskeleton adhesion
1Department of Biological Sciences, PO Box 2408, Columbia University, Sherman Fairchild Center, 1212 Amsterdam Avenue, New York, NY 10027, USA. ms2001@columbia.edu
Nature Reviews. Molecular Cell Biology
|May 2, 2001
Abstract:
The rates of mechanochemical processes, such as endocytosis, membrane extension and membrane resealing after cell wounding, are known to be controlled biochemically, through interaction with regulatory proteins. Here, I propose that these rates are also controlled physically, through an apparently continuous adhesion between plasma membrane lipids and cytoskeletal proteins.
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