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Reactive thrombocytosis in children with upper urinary tract infections
A Garoufi1, K Voutsioti, H Tsapra
1Second Department of Paediatrics P. & A. Kyriakou Children's Hospital, Athens, Greece. garoufi@hotmail.com
Insights
Reactive thrombocytosis, an elevated platelet count, is common in children with upper urinary tract infections, particularly during recovery. Lower urinary tract infections showed a much lower incidence of this condition.
Area of Science:
- Pediatric infectious diseases
- Hematology
Background:
- Urinary tract infections (UTIs) are common in children.
- Reactive thrombocytosis, an increase in platelet count, can occur during infections.
Purpose of the Study:
- To investigate the association between reactive thrombocytosis and the severity of urinary tract infections in pediatric patients.
Main Methods:
- Platelet counts were monitored in 48 children before, during, and after treatment for UTIs.
- Infection severity was categorized as upper or lower UTIs.
Main Results:
- Reactive thrombocytosis was observed in 74% of children with upper UTIs.
- Only 14% of children with lower UTIs exhibited reactive thrombocytosis.
- An additional 15% of children with upper UTIs showed a significant platelet count increase.
Conclusions:
- Reactive thrombocytosis is strongly linked to upper UTIs, specifically renal parenchymal infections.
- This hematological finding typically manifests during the recovery phase of these infections.
Unlabelled:
The relationship between reactive thrombocytosis and the level of urinary tract infections was studied in 48 children. Platelets were counted before, during and after treatment. Reactive thrombocytosis was noticed in 74% of children with upper and in 14% with lower urinary tract infections. A significant rise in the platelet count presented in another five children (15%) with upper urinary tract infections.
Conclusion:
Reactive thrombocytosis was found almost exclusively in the renal parenchymal infections, usually during the recovery phase.