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Updated: Aug 3, 2026

Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction
Published on: May 28, 2019
Leukodepletion and aprotinin improve clinical outcome after extracorporeal circulation
1Fuqua Heart Center, Piedmount Hospital, Atlanta, Georgia 30309, USA. gottjp@aol.com
Abstract:
Most cardiac operations involve the use of extracorporeal circulation with its attendant systemic inflammatory response syndrome. Many anti-inflammatory strategies hold promise for reducing the associated morbidity of cardiopulmonary bypass. The application of pharmacological and mechanical strategies to control this inflammatory response now has demonstrable clinical benefit. The additional costs of these successful strategies are offset by the economic savings and improved quality of care.
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