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Development of severe longitudinal atrophy of thoracic spinal cord following lupus-related myelitis

S Yazawa1, S Kawasaki, T Ohi

  • 1Department of Neurology, Miyazaki Prefectural Hospital of Nobeoka.

Internal Medicine (Tokyo, Japan)
|May 4, 2001
PubMed

A 26-year-old woman suffered from acute myelitis at Th 6 level associated with systemic lupus erythematosus. Methyl-prednisolone pulse therapy, intravenous high-dose immunoglobulin administration and plasmapheresis were not effective. Her neurological signs had persisted in spite of subsequent administration of oral prednisolone and azathiopurine. Magnetic resonance imaging (MRI) of spinal cord at the onset showed a marked swelling with intramedullary high intensity signals on T2WI along the whole thoracic cord. Three years later, MRI demonstrated a severe longitudinal and segmental atrophy of the mid to low thoracic cord which resulted in transverse spinal signs.

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