Timed-release tablets containing quinine sulfate

The release rates of quinine sulfate from slowly eroding, timed-release tablets prepared with various amounts of a swellable gum, carbomer, and cellulose acetate hydrogen phthalate at different compaction pressures were attained. For the dissolution test of the prepared tablets, the method described in NF XIII was followed. The concentration of the released quinine sulfate was determined spectrophotometrically.