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PNA oligomers as tools for specific modulation of gene expression

M Pooga1, T Land, T Bartfai

  • 1Department of Neurochemistry and Neurotoxicology, Arrhenius Laboratories, Stockholm University, S-10691 Stockholm, Sweden.

Biomolecular Engineering
|May 5, 2001
PubMed
Summary

Peptide nucleic acids (PNA) are stable oligonucleotide mimics that effectively inhibit gene expression. PNAs show promise as long-lived antisense/antigene drugs for both in vitro and in vivo applications.

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