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Updated: Jul 29, 2026

Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
Published on: November 2, 2013
Prostate-specific antigen-all that rises is not refractory
B L Hintz1, A Van Nieuwenhuize, A R Kagan
1Department of Radiation Oncology, Southern California Permanente Medical Group, Los Angeles, California, USA.
Abstract:
After the initiation of androgen suppression in men with prostate cancer, the serum prostate-specific antigen (PSA) level generally declines. A subsequent PSA rise during that suppression usually reflects the presence of a significant component of hormonally refractory prostate cancer. We report a patient with a rising PSA level and elevated testosterone level after depot leuprolide in whom the PSA level subsequently declined with administration of bicalutamide.

