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Updated: Aug 15, 2026

Intubation-mediated Intratracheal (IMIT) Instillation: A Noninvasive, Lung-specific Delivery System
Published on: November 17, 2014
Application of the self-inflating bulb to a hollow intubating introducer
1I Servizio di Anestesia e Rianimazione, Spedali Civili, Brescia, Italy. danieletuzzo@hotmail.com
Background:
The aspiration test, performed by a self-inflating bulb (SIB), is a simple and reliable method to detect an accidental esophageal intubation. The aim of the study, in case of employment of a hollow intubating introducer (HII), was to verify the possibility to directly perform the test with the introducer and its efficacy in allowing the detection of its position.
Experimental Design:
prospective, randomized study.
Environment:
operating theater in a university hospital.
Patients:
adult patients, without evidence of gastro-esophageal or tracheobronchial pathologies, scheduled for elective surgery.
Interventions:
patients were randomized in two groups T (HII was placed in trachea) and E (HII was positioned in the esophagus). Under general anesthesia, a HII was placed in either the trachea or the esophagus. A blinded anesthesiologist connected the SIB to the HII and performed the test twice.
Measurements:
the anesthesiologist inferred the position of the device, based on the re-inflation observed.
Results:
One hundred subjects were studied. In group E patients, a prompt and complete re-inflation of the bulb was never observed and the anesthesiologist correctly inferred the position of the HII. Occasionally (3.5% of cases), in group T patients, a prevented or incomplete re-inflation of the bulb occurred, leading to an incorrect judgment of the HII position.
Conclusions:
The aspiration test with the SIB allows the proper detection of the introducer in esophagus. When used in combination with a HII, both time and local trauma associated with an erroneous, introducer-guided esophageal intubation in case of difficult laryngoscopy may be reduced.
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