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Related Experiment Videos

Hearing loss in progressive systemic sclerosis patients: a comparative study.

I Kastanioudakis1, N Ziavra, E N Politi

  • 1Department of Otolaryngology, Medical School, University of Ioannina, Greece.

Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
|May 5, 2001
PubMed
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Progressive systemic sclerosis (PSS) can cause hearing loss in one-fourth of patients, primarily affecting high frequencies. A notable percentage also exhibit patulous Eustachian tubes, warranting further research into ear damage mechanisms.

Area of Science:

  • Otolaryngology
  • Rheumatology
  • Audiology

Background:

  • Progressive systemic sclerosis (PSS) is a multisystem autoimmune disease.
  • Potential audiovestibular complications in PSS are not fully understood.

Purpose of the Study:

  • To investigate the prevalence and characteristics of middle and inner ear involvement in patients with PSS.
  • To assess audiological function and Eustachian tube status in PSS patients.

Main Methods:

  • Prospective evaluation of 34 PSS patients.
  • Comprehensive audiological assessments including pure tone, impedance, and speech audiometry.
  • Recording of systemic disease manifestations, drug therapy, and autoantibody status; comparison with 45 healthy controls.

Main Results:

Related Experiment Videos

  • Sensorineural hearing loss observed in 20% of PSS patients; mixed hearing loss in 3.3%.
  • Hearing loss did not correlate with age, disease activity, autoantibodies, or medication.
  • Patulous Eustachian tubes found in 10% of patients.

Conclusions:

  • Approximately 25% of PSS patients experience hearing loss, mainly affecting high frequencies.
  • A significant prevalence of bilateral patulous Eustachian tubes was identified.
  • Further research is necessary to elucidate the mechanisms of otologic damage in PSS.