[Experience in chemotherapy of tuberculosis in children based on WHO recommendations]

WHO recommends that patients with primary intrathoracic tuberculosis fall into 4 categories by clinical symptoms, severity and spread of the process. They are to receive 2 staged treatment. The duration of each chemotherapy phase depends on the time of reverse development of the specific process regarding abacillarity of the primary tuberculosis by clinicoroentgenological dynamics. Therapy in children is completed after a full resolution of the pathological changes or upon stabilization of the process at the stage of residual changes when clinical laboratory evidence indicates absence of latent activity of the process. According to these WHO criteria 255 children aged 3 to 12 years were treated in the Central Research Institute of Tuberculosis for the last 10 years.