Related Experiment Video
Updated: Aug 8, 2026

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection
Published on: December 8, 2014
Necrotizing fasciitis in Crohn's disease
S J Panter1, M G Bramble, J R Bell
1South Cleveland Hospital, Middlesbrough, UK. simonpanter@doctors.org.uk
Necrotizing fasciitis is a rare but serious complication of Crohn's disease, particularly when a fistulous tract is involved. This case highlights the importance of recognizing this potential risk in patients with complex gastrointestinal conditions.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Surgical Pathology
Background:
- Crohn's disease is a chronic inflammatory bowel condition.
- Fistulating Crohn's disease involves abnormal connections between the bowel and other organs or skin.
- Necrotizing fasciitis is a severe bacterial infection of the soft tissues.
Observation:
- A 34-year-old woman with Crohn's disease presented with anemia and sacroiliac pain.
- A fistulous tract was identified as the likely route of pathogen entry.
- The patient subsequently developed necrotizing fasciitis.
Findings:
- This case represents the first reported instance of necrotizing fasciitis complicating fistulating Crohn's disease.
- The infection was introduced via a fistulous tract associated with Crohn's disease.
- The clinical presentation included anemia and sacroiliac joint pain preceding the fasciitis.
Implications:
- This case underscores the potential for severe infectious complications in patients with fistulating Crohn's disease.
- Early recognition and management of necrotizing fasciitis are critical in this patient population.
- Further research may be warranted to understand the incidence and risk factors for this rare complication.
Related Concept Videos
Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents
Drugs for Treatment of Crohn's Disease in IBD Using Biologic Agents: Anti-TNF
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Inflammatory Bowel Disease I: Introduction
Inflammatory Bowel Disease III: Crohn's Disease
Inflammatory Bowel Disease IV: Clinical Manifestations

