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Behaviour of 2-substituted 1,3-indandiones towards aldimines
E M Afsah1, W S Hamama, H A Etman
1Chemistry Department, Faculty of Science, Mansoura University, Mansoura, Egypt.
Bollettino Chimico Farmaceutico
|May 8, 2001
Abstract:
Treatment of 2-cyano-1,3-indandione (1) with aldimines gave the expected Mannich bases (2-4), while the arylidenes (7,8) were obtained when 2-ethoxycarbonyl-1,3-indandione (5) was subjected to react with aldimines. On the other hand, treatment of 2-acetyl-1,3-indandione (9) with aldimines gave compounds (11,12,14). The reaction of 2-phenyl-1,3-indandione (15) with aldimines gave the arylamino and the ethylene diamino derivatives (17, 18). Pictet Spengler reaction of 19b gave the spiro compound (21).