Related Experiment Video
Updated: Aug 15, 2026
Using Coculture to Detect Chemically Mediated Interspecies Interactions
Published on: October 31, 2013
[Specificity of sensitivity to mycocin from Tilletiopsis flava BKM Y-2838]
1All-Russia Collection of Microorganisms, Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, pr. Nauki 5, Pushchino, Moscow Oblast, 142290 Russia.
Abstract:
The mycocinogenous strain Tilletiopsis flava VKM Y-2823 was found to possess fungicidal activity at pH 3.5-4.5, which was retained after curing the strain by eliminating the extrachromosomal genetic elements. The mycocin produced by the strain had a molecular mass of more than 10 kDa and was readily inactivated by heating and treatment with protease K. This mycocin was found to be active against species of the anamorphic genus Tilletiopsis. The overwhelming majority of other representatives of the order Tilletiales, as well as ascomycetous and basidiomycetous yeasts, which either form or did not from ballistospores of the orders Sporidiales and Tremellales, were resistant to it.
