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Related Experiment Videos

[Fibroblastic rheumatism: a case report].

B Chkirate1, C Job-Deslandre

  • 1Service de pédiatrie IV, hôpital d'Enfants, centre hospitalier universitaire, lbn Sina, Rabat, Maroc.

Archives De Pediatrie : Organe Officiel De La Societe Francaise De Pediatrie
|May 8, 2001
PubMed
Summary

Fibroblastic rheumatism is a rare condition, with juvenile onset being exceptionally uncommon. This case highlights its potential to cause erosive arthritis in children, necessitating consideration in differential diagnoses.

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Area of Science:

  • Rheumatology
  • Pediatric Rheumatology
  • Histopathology

Background:

  • Fibroblastic rheumatism is a rare condition characterized by nodules and arthropathy.
  • Literature review indicates only 19 reported cases, with a single prior pediatric case.
  • The etiology and pathogenesis of fibroblastic rheumatism remain largely unknown.

Observation:

  • A pediatric patient presented with nodules on the elbows, tibia, metacarpophalangeal (MCP), and proximal interphalangeal (PIP) joints.
  • The patient developed arthralgia and stiffness in wrists and toes, with X-rays revealing destructive and erosive lesions.
  • Histological examination of nodules confirmed the diagnosis of fibroblastic rheumatism.

Findings:

  • The diagnosis of fibroblastic rheumatism relies on characteristic nodule histology.

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  • Erosive arthropathy is an infrequent manifestation, observed in 8 out of 15 adult cases.
  • This case represents the second reported instance of juvenile-onset fibroblastic rheumatism.

    • Implications:

    • Fibroblastic rheumatism should be considered in the differential diagnosis of juvenile arthritis with erosive features.
    • The rarity of this condition underscores the need for further research into its mechanisms and treatment.
    • Established therapeutic strategies for fibroblastic rheumatism are limited due to its infrequent occurrence.