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Ethnic variation in fluorescein angiography induced nausea and vomiting
R McLauchlan1, H Waterman, C Waterman
1Retinal Medical Unit, Manchester Royal Eye Hospital, UK.
Purpose:
A prospective survey was undertaken to investigate ethnic variations in the frequency of nausea and vomiting after fundus fluorescein angiography (FFA).
Method:
Between May and September 1998, 197 adult patients were recruited to the study. A questionnaire containing closed-ended questions was completed by nurses after each FFA and a questionnaire was given to patients to complete 5 hours after the procedure at home. Patients' anxiety level was measured before FFA using a 5-item ordinal response scale.
Results:
Results indicate that patients from black, Asian, Chino-Asian and mixed ethnic origins are significantly more likely to vomit and feel nauseous immediately after the administration of fluorescein dye. Patients with a history of nausea after FFA are significantly more likely to feel nauseous again after repeat FFA.
Conclusion:
Ethnic origin and a previous history of nausea and vomiting appear to be important factors in FFA-induced nausea and vomiting. The results of this study have led the investigators to develop a protocol for the prophylactic treatment of nausea and vomiting following FFA.