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Updated: Jul 11, 2026

An In Vitro Model for the Study of Cellular Pathophysiology in Globoid Cell Leukodystrophy
Published on: October 21, 2014
A theory of cellular-function pathology: further development of Virchow's theory of cellular pathology
1Princeton Biotechnologies, Princeton, New Jersey 08540, USA.
Abstract:
A new theory of pathology is introduced. The human cell is an organism in itself. It fulfills both cell-oriented and organism-oriented functions. Impairment of either one of these functions may lead to disease. This means that a structural lesion of a cell is not a sole and necessary cause of the beginning of disease. When a cell-oriented function is impaired the cell suffers, but the overt symptoms at the organ-organism level might be absent for a very long time. This is how a chronic asymptomatic disease starts. Measures of prophylaxis, diagnosis, and treatment should be centered upon maintenance and restoration of a balance between the cell-oriented and organism-oriented cellular functions.
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