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Electrical properties of a light-addressable microelectrode chip with high electrode density for extracellular
V Bucher1, B Brunner, C Leibrock
1Natural and Medical Sciences Institute, Markwiesenstrasse 55, D-72770, Reutlingen, Germany. bucher@nmi.de
Abstract:
A light-addressable microelectrode chip with 3600 TiN electrodes was fabricated. Amorphous silicon (a-Si:H) serves as a photo conductor. The electrodes on the chip are addressed by a laser spot and electrical properties of the system are determined. DC measurements show a dark to bright dynamic of 10(6)-10(7). The AC impedance dynamic @ 1 kHz/100 mV and thus the signal-to-noise-ratio is determined to 60. This value is quite sufficient for electrophysiological measurements. For the first time, recordings from cardiac myocytes are reported using the principle of light-addressing. Measurements were done with a standard laser scan microscope (Zeiss LSM 410).
