Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Chiropractic manipulation and stroke: a population-based case-control study.

D M Rothwell1, S J Bondy, J I Williams

  • 1Institute for Clinical Evaluative Sciences, University of Toronto, Toronto,Ontario, Canada.

Stroke
|September 6, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Milestones in the natural course of the onset of e-cigarette dependence among adolescents and young adults: Retrospective study.

Addictive behaviors·2023
Same author

Research abstracts presented at the Eastern Allergy Conference, Palm Beach, Florida, May 6-9, 2010.

Allergy and asthma proceedings·2017
Same author

Abstracts from the North American Rhinology & Allergy Conference, February 3, 2011, Puerto Rico.

American journal of rhinology & allergy·2017
Same author

Identifying cases of congestive heart failure from administrative data: a validation study using primary care patient records.

Chronic diseases and injuries in Canada·2013
Same author

Assessing the reach of nicotine replacement therapy as a preventive public health measure.

Chronic diseases and injuries in Canada·2013
Same author

Air quality, mortality, and economic benefits of a smoke - free workplace law for non-smoking Ontario bar workers.

Indoor air·2012
Same journal

Defining the Therapeutic Ceiling of Endovascular Thrombectomy in Large-Core Stroke: Beyond the Limits of ASPECTS.

Stroke·2026
Same journal

Adjunctive Normobaric Hyperoxia With Endovascular Thrombectomy for Acute Stroke at 6 to 24 Hours: A Phase IIb Randomized Trial.

Stroke·2026
Same journal

Management of Patients at Risk of Ischemic Stroke With Left Ventricular Systolic Dysfunction in the Absence of Intracardiac Thrombus: A Scientific Statement From the American Heart Association.

Stroke·2026
Same journal

Update on Rehabilitation After Stroke: Global Changes and the Continued Importance of Therapy Intensity, Dose, and Timing.

Stroke·2026
Same journal

ENTF Neuromodulation Yields Reduced Disability After Stroke: An Individual Participant-Level Data Meta-Analysis.

Stroke·2026
Same journal

Menopause and Its Implications for Stroke in Women.

Stroke·2026
See all related articles

Chiropractic neck manipulation may be linked to vertebrobasilar accidents (VBAs) in young adults. This study found a higher likelihood of chiropractic visits before VBA events in individuals under 45. Further research is recommended.

Area of Science:

  • Neurology
  • Public Health
  • Epidemiology

Background:

  • Previous studies on chiropractic neck manipulation and vertebral artery dissection/occlusion relied on uncontrolled case series.
  • A population-based nested case-control study was designed to investigate this association more rigorously.

Purpose of the Study:

  • To test the association between chiropractic manipulation of the neck and vertebrobasilar accidents (VBAs).
  • To evaluate the risk in different age groups.

Main Methods:

  • Hospitalization records identified 582 VBA cases in Ontario, Canada (1993-1998).
  • Cases were matched to 4 controls without stroke history.
  • Chiropractic service use was documented via public health insurance billing records prior to the VBA event.

Related Experiment Videos

Main Results:

  • Younger adults (<45 years) with VBA were 5 times more likely to have visited a chiropractor within one week of the event.
  • In the younger group, cases were also 5 times more likely to have had 3 or more chiropractic visits with a cervical diagnosis in the month preceding the VBA.
  • No significant association was found for individuals aged 45 years or older.

Conclusions:

  • The analysis suggests a potential association between chiropractic manipulation and VBA in young adults.
  • Potential sources of bias were discussed, acknowledging the rarity of VBAs.
  • High-quality research on the risks and benefits of spinal manipulation is recommended due to its popularity.