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Published on: April 21, 2012
[Growth retardation in children with positive intradermic reaction for leishmaniasis: preliminary results]
D F Cunha1, V C Lara, J P Monteiro
1Disciplina de Nutrologia, Departamento de Clínica Médica, Faculdade de Medicina do Triângulo Mineiro, Uberaba, MG. dfcnutro@mednet.com.br
Insights
Children with a positive Montenegro (leishmanin) test showed higher stunting rates. This suggests Leishmania infection negatively impacts child nutritional status, despite similar food intake.
Area of Science:
- Public Health
- Tropical Medicine
- Pediatrics
Background:
- Leishmaniasis is a significant public health concern in endemic areas.
- Nutritional status is crucial for child development and immune function.
Purpose of the Study:
- To compare growth retardation and food intake in children with and without positive Montenegro (leishmanin) tests in Brazil.
- To investigate the impact of Leishmania infection on children's nutritional status.
Main Methods:
- A comparative study was conducted in Porteirinha town, Brazil.
- 24-hour food intake recalls assessed daily nutrient consumption.
- Anthropometric data were compared against World Health Organization (WHO) standards.
- Children were categorized into Montenegro-positive (n=9) and Montenegro-negative (n=17) groups.
Main Results:
- No significant differences in age, daily energy intake, or protein consumption were observed between groups.
- Montenegro-positive children exhibited a substantially higher prevalence of stunting (44.4%) compared to Montenegro-negative children (5.9%).
Conclusions:
- Previous Leishmania sp. infection appears to have a detrimental effect on the nutritional status of children.
- Stunting in Montenegro-positive children indicates potential long-term growth consequences of leishmaniasis.
- Further research is warranted to elucidate the mechanisms linking Leishmania infection and growth retardation.
Abstract:
The objective of this study was to compare growth retardation frequency, and 24-h food intake data of children with or without positive Montenegro (leishmanin) test, examined in Porteirinha town, Brazil. Daily nutrient intake was determined by 24-h food intake recall and the anthropometric data were compared to the standard values from WHO. Montenegro-positive (n = 9) and Montenegro-negative (n = 17) groups showed similar age (5.5 +/- 1.9 vs 6.7 +/- 2.3y), and energy (1,456.8 +/- 314.8 vs 1,316.2 +/- 223.8kcal) and protein (50.4 +/- 16.7 vs 49.9 +/- 13.9g) daily consumption, respectively. Montenegro-positive children had higher percentage of stunting than their Montenegro-negative counterparts (44.4 vs 5.9), suggesting that previous Leishmania sp infection had negative impact on children's nutritional status.
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