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[Transitional cell carcinoma in a young heavy marihuana smoker]
P Moiche Bokobo1, M A Atxa de la Presa, J Cuesta Angulo
1Departamento de Urología, Hospital Príncipe de Asturias, Alcalá de Henares, Madrid, España.
Objective:
To report a case of low grade papillary transitional cell carcinoma of the left renal pelvis in a young, heavy smoker of marihuana who denied cocaine use, alcohol intake and other habits.
Methods/Results:
Intravenous pyelogram demonstrated a filling defect in the left renal pelvis and calyces. Biopsy revealed a urothelial carcinoma. The pathological analysis demonstrated diffuse low-grade non-invasive (Ta) papillary transitional cell carcinoma of the renal pelvis and calyces. Nephroureterectomy was performed.
Conclusions:
This case indicates a cause-effect relationship between heavy and long-term marihuna smoking and transitional cell cancer. However, further cases from the literature or observations in larger populations are warranted.