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Related Experiment Video

Updated: Jun 25, 2026

Assessment of Vascular Tone Responsiveness using Isolated Mesenteric Arteries with a Focus on Modulation by Perivascular Adipose Tissues
08:41

Assessment of Vascular Tone Responsiveness using Isolated Mesenteric Arteries with a Focus on Modulation by Perivascular Adipose Tissues

Published on: June 3, 2019

Mesenteric Vascular Disease.

Bruce H. Gray1, Timothy M. Sullivan

  • 1Upstate Vascular Associates, Greenville Memorial System, 890 West Faris Road, Greenville, SC 29615, USA. bhgray@ghs.org

Current Treatment Options in Cardiovascular Medicine
|May 9, 2001
PubMed
Summary
This summary is machine-generated.

Mesenteric ischemia treatment varies by cause and stage. Early intervention with medical or endovascular methods is key, while advanced cases require surgery for bowel infarction.

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Area of Science:

  • Vascular Surgery
  • Gastroenterology
  • Interventional Radiology

Background:

  • Mesenteric ischemia presents with diverse clinical manifestations.
  • Early diagnosis and intervention are crucial for favorable outcomes.
  • Treatment strategies are dictated by the specific type and stage of ischemia.

Purpose of the Study:

  • To outline the clinical presentation and management of various forms of mesenteric ischemia.
  • To differentiate treatment approaches based on the underlying cause and disease progression.
  • To highlight the efficacy of medical, endovascular, and surgical interventions.

Main Methods:

  • Review of clinical presentations of mesenteric ischemia.
  • Analysis of treatment modalities including medical, endovascular, and surgical options.
  • Categorization of interventions based on ischemia type (acute, chronic, venous, non-occlusive) and severity.

Main Results:

  • Early-stage ischemia benefits from medical and endovascular therapies.
  • Peritonitis signals bowel infarction, necessitating surgical exploration and resection.
  • Chronic mesenteric ischemia from arteriosclerosis is managed with angioplasty and stenting (PTAS) or bypass surgery.
  • Acute embolic/thrombotic ischemia requires surgical treatment post-resuscitation; endovascular methods are for selected subacute cases.
  • Non-occlusive ischemia demands correction of hypotension/sepsis and papaverine infusion.
  • Celiac artery compression syndrome is treated surgically; PTAS is contraindicated.
  • Mesenteric venous occlusion is managed with anticoagulation.

Conclusions:

  • Tailored treatment strategies are essential for effective management of mesenteric ischemia.
  • Timely intervention, ranging from medical management to surgical resection, improves patient outcomes.
  • Distinguishing between ischemic causes and stages guides the selection of optimal therapeutic approaches.