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Isolation and expression of a gene (CGR1) regulated during the yeast-hyphal transition in Candida albicans
1Department of Oral Microbiology, Fukuoka Dental College, 2-15-1 Tamura, Sawara-ku, Fukuoka 814-0193, Japan. chot1@college.fdcnet.ac.jp
Biochimica Et Biophysica Acta
|May 9, 2001
Abstract:
We used RNA fingerprinting of arbitrarily primed PCR to isolate genes upregulated during the yeast-hyphal transition in Candida albicans. The sequence and expression of one of these genes (CGR1, Candida growth regulation) are presented. Our results suggest that CGR1 expression is associated with a growth cessation of yeast cells, a prerequisite for germination in this organism.