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Updated: Oct 7, 2026

Coulomb Explosion Imaging as a Tool to Distinguish Between Stereoisomers
Published on: August 18, 2017
One-wedge convention for stereochemical representations
1Molecular Diversity Preservation International (MDPI), Saengergasse 25, CH-4054 Basel, Switzerland. lin@mdpi.org
Abstract:
We propose that various bonds (see figure below) used for specification of absolute configuration, e.g. the two types (I and II) of solid wedge and broken wedge representation most frequently seen in literature, can be replaced by only one kind of wedge, namely the solid wedge (III and IV). Only one wedge should be used when representing a quadrivalent center (IV). The three normal bonds are distributed on a cone opposite to the wedge. The flexibility, simplicity, unambiguity and usefulness for R-S specification of the one-wedge system are discussed, as well as its esthetic appeal.
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