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Related Experiment Videos

Soft tissue sarcomas involving the pelvis.

S J Lewis1, J S Wunder, J Couture

  • 1University Musculoskeletal Oncology Unit, Mount Sinai Hospital, Department of Surgical Oncology, Toronto, Ontario, Canada.

Journal of Surgical Oncology
|May 10, 2001
PubMed
Summary

Pelvic soft tissue sarcomas (STS) are rare and aggressive. Despite surgery and radiation, these tumors show a high risk of recurrence and spread, impacting patient outcomes.

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Area of Science:

  • Oncology
  • Surgical Oncology
  • Radiology

Background:

  • Soft tissue sarcomas (STS) of the true pelvis are rare.
  • Limited literature exists on pelvic STS, hindering treatment planning and outcome prediction.

Purpose of the Study:

  • To understand the anatomical extension of pelvic STS.
  • To guide surgical treatment strategies.
  • To determine patient outcomes for pelvic STS.

Main Methods:

  • Retrospective review of 18 consecutive patients with pelvic STS (1987-1995).
  • Minimum follow-up of 18 months.
  • Cross-sectional imaging analyzed for tumor location and extension.

Main Results:

  • Tumor extension varied: true pelvis (4), retroperitoneum (3), thigh (11).

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  • Most patients received adjuvant radiation and surgical resection (local or hindquarter amputation).
  • High morbidity, positive resection margins (9/18), and poor survival observed (11 deaths, 4 alive with disease, 3 alive without disease).

    • Conclusions:

    • Pelvic STS is a rare but aggressive malignancy.
    • High risk of local and systemic disease progression persists despite combined modality treatment.