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Related Experiment Videos

Metaldehyde poisoning in three horses.

W F Harris

    Modern Veterinary Practice
    |May 1, 1975
    PubMed
    Summary

    Metaldehyde poisoning in horses causes severe nervous and cardiopulmonary signs, often leading to death within hours. Even small ingestions can be fatal, highlighting the acute toxicity of this pesticide in equine patients.

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    Area of Science:

    • Veterinary Toxicology
    • Equine Medicine
    • Animal Health

    Background:

    • Metaldehyde is a common pesticide used in agriculture.
    • Accidental ingestion of pesticides can pose significant risks to animal health.
    • Understanding the toxic effects of metaldehyde in horses is crucial for prompt diagnosis and treatment.

    Purpose of the Study:

    • To document the clinical signs and outcomes of metaldehyde poisoning in horses.
    • To investigate the acute toxicity of metaldehyde following ingestion in equine cases.
    • To provide data on the rapid progression of clinical manifestations and mortality.

    Main Methods:

    • Case series reporting on three horses with suspected metaldehyde ingestion.
    • Clinical examination focusing on neurological and cardiopulmonary parameters.
    • Dosage determination based on owner reports and case history.
    • Necropsy findings were not detailed in the provided abstract.

    Main Results:

    • Horses exhibited pronounced nervous system (tremors, seizures) and cardiopulmonary (dyspnea, tachycardia) signs.
    • Rapid onset of severe clinical manifestations occurred within hours of ingestion.
    • Mortality was high, with two of three horses dying within 3 to 5 hours post-ingestion.
    • A colt experimentally administered 0.1 mg/kg metaldehyde also succumbed rapidly.

    Conclusions:

    • Metaldehyde is highly toxic to horses, even in small amounts.
    • Rapid veterinary intervention is critical for horses suspected of metaldehyde ingestion.
    • The study underscores the potential for fatal outcomes due to acute metaldehyde toxicity in equines.

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