Related Experiment Video
Updated: Aug 13, 2026

In Vitro Model of Human Cutaneous Hypertrophic Scarring using Macromolecular Crowding
Published on: May 1, 2020
Hypertrophic scars and keloids
1Division of Podiatric Surgery, Department of Surgery, University of Calgary, Faculty of Medicine, Calgary, Alberta, Canada.
Abstract:
Excessive scarring caused by pathologically overabundant collagen deposition is a problem known by all surgeons. Complications to wound healing, such as hypertrophic scars and keloids, can lead to an aesthetically unacceptable result or even lead to anatomic dysfunction. An overwhelming amount of hypotheses concerning treatment of these problems is available. There seems to be no absolutely effective treatment for hypertrophic scars and keloids and the number of treatment modalities illustrate the lack of understanding concerning this kind of pathologic scar healing. Most studies reported have not been well controlled and have produced conflicting results.
Related Concept Videos
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Cellular Adaptation II: Hypertrophy
Cellular Adaptation III: Hyperplasia
Chronic Inflammation: Introduction
Healing II: Complications
Cirrhosis I: Introduction

