Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Dopamine agonists.

P Tuite1, B Ebbitt

  • 1Department of Neurology, University of Minnesota, Minneapolis 55455, USA.

Seminars in Neurology
|May 11, 2001
PubMed
Summary
This summary is machine-generated.

Dopamine agonists effectively treat Parkinson's disease across all stages. This review compares their pros and cons against levodopa, detailing approved and investigational agents.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

McLeod syndrome: Five new pedigrees with novel mutations.

Parkinsonism & related disorders·2019
Same author

Clinical vignettes in Parkinson's disease: a collection of unusual medication-induced hallucinations, delusions, and compulsive behaviours.

The International journal of neuroscience·2011
Same author

Inferior olive response to passive tactile and visual stimulation with variable interstimulus intervals.

Cerebellum (London, England)·2010
Same author

Altered diffusion in the frontal lobe in Parkinson disease.

AJNR. American journal of neuroradiology·2008
Same author

Selective impairments in implicit learning in Parkinson's disease.

Brain research·2007
Same author

Hypertrophic olivary degeneration: metaanalysis of the temporal evolution of MR findings.

AJNR. American journal of neuroradiology·2000
Same journal

Isolated Cranial Tremors: A Reappraisal.

Seminars in neurology·2026
Same journal

Dystonia and Tremor.

Seminars in neurology·2026
Same journal

Pendular nystagmus and oculopalatal tremor.

Seminars in neurology·2026
Same journal

Sanjay Pandey, MBBS, MD, DNB, DM, FIAN, and Aasef Shaikh, MD, PhD.

Seminars in neurology·2026
Same journal

Tremor.

Seminars in neurology·2026
Same journal

Carotid Disease.

Seminars in neurology·2026
See all related articles

Area of Science:

  • Neurology
  • Pharmacology

Background:

  • Parkinson's disease (PD) is a progressive neurodegenerative disorder.
  • Dopamine deficiency is a key pathological feature of PD.
  • Current treatments aim to restore dopaminergic neurotransmission.

Purpose of the Study:

  • To compare dopamine agonists with levodopa therapy for Parkinson's disease.
  • To review the features and costs of available dopamine agonists.
  • To discuss the role of dopamine agonists in early, middle, and late-stage PD.

Main Methods:

  • Comparative review of therapeutic options.
  • Analysis of pharmacological properties.
  • Discussion of clinical trial data and cost-effectiveness.

Main Results:

Related Experiment Videos

  • Dopamine agonists offer an alternative to levodopa for PD management.
  • Specific agonists (bromocriptine, pergolide, pramipexole, ropinirole) and apomorphine are evaluated.
  • Advantages and disadvantages relative to levodopa are presented.

Conclusions:

  • Dopamine agonists are valuable in all stages of Parkinson's disease.
  • Therapeutic choice depends on individual patient factors and drug characteristics.
  • Further investigation of agents like apomorphine is ongoing.