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Dry eye in the elderly.

M A Terry1

  • 1Corneal Services, Devers Eye Institute, Portland, Oregon 97210-3065, USA. MTerry@discoveriesinsight.org

Drugs & Aging
|May 11, 2001
PubMed
Summary
This summary is machine-generated.

Dry eye in older adults involves complex tear film dysfunction. Emerging research suggests dry eye is an inflammatory condition, with topical cyclosporine showing promising results for relief.

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Area of Science:

  • Ophthalmology
  • Geriatric Medicine

Background:

  • Dry eye disease (DED) is prevalent in the elderly, stemming from multifactorial causes affecting the tear film.
  • The tear film's integrity relies on meibomian glands, lacrimal glands, goblet cells, and proper eyelid function.

Purpose of the Study:

  • To review the contributing factors, current treatments, and emerging therapeutic paradigms for dry eye in the elderly.
  • To highlight the potential of viewing dry eye as a subclinical inflammatory condition.

Main Methods:

  • Literature review of dry eye pathophysiology and therapeutic approaches.
  • Analysis of current management strategies including artificial tears, ointments, and tear drainage occlusion.
  • Evaluation of novel treatments, such as topical cyclosporine.

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Main Results:

  • Dysfunction of tear film components or eyelid closure leads to dry eye symptoms like burning and blurred vision.
  • Current treatments focus on tear augmentation and drainage management.
  • Topical cyclosporine demonstrates encouraging preliminary results for managing inflammatory dry eye.

Conclusions:

  • Dry eye in the elderly is a complex condition requiring comprehensive management.
  • A paradigm shift towards understanding dry eye as an inflammatory disease is emerging.
  • Future advancements in treatment offer hope for patients with chronic dry eye.