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Iatrogenic ejaculation disorders and their prevention.

C Terrone1, E Castelli, P Aveta

  • 1Clinica Urologica, Università degli Studi, Turin, Italy.

Minerva Urologica E Nefrologica = the Italian Journal of Urology and Nephrology
|May 11, 2001
PubMed
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Retroperitoneal lymphadenectomy for testis cancer can cause ejaculation disorders. Nerve-sparing techniques and unilateral procedures significantly improve ejaculation preservation rates in patients.

Area of Science:

  • Urology
  • Surgical Oncology
  • Reproductive Medicine

Background:

  • Ejaculation is controlled by sympathetic nerves from the D10-L2 medullar center, forming the superior hypogastric plexus.
  • Retroperitoneal lymphadenectomy (RL) for testis cancer is a significant cause of ejaculation disorders in young patients.
  • Previous research focused on lymph node dissection techniques to minimize ejaculation loss.

Purpose of the Study:

  • To evaluate the impact of retroperitoneal lymphadenectomy on ejaculation in testis cancer patients.
  • To analyze the effectiveness of different RL approaches (bilateral, unilateral) in preserving ejaculation.
  • To discuss the applicability of ejaculation-sparing surgical concepts to other retroperitoneal procedures.

Main Methods:

  • Retrospective analysis of 41 patients who underwent RL for testis cancer between 1983 and 1998.

Related Experiment Videos

  • Categorization of patients based on the extent of RL (bilateral vs. unilateral).
  • Assessment of ejaculation function post-surgery.
  • Main Results:

    • Overall survival rate was 95.2%.
    • In patients undergoing bilateral RL, only 33% preserved ejaculation.
    • 100% of patients with right monolateral RL and 70% with left monolateral RL preserved ejaculation.

    Conclusions:

    • Unilateral retroperitoneal lymphadenectomy significantly preserves ejaculation function compared to bilateral procedures.
    • Ejaculation-sparing surgical principles from RL can be applied to other retroperitoneal surgeries.
    • Various factors, including BPH treatment and certain medications, can also lead to ejaculation disorders.