Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Toward a new method of analyzing cardiac performance.

C M Ripplinger1, D L Ewert, S C Koenig

  • 1Department of Electrical and Computer Engineering, North Dakota State University, Fargo, ND 58105, USA.

Biomedical Sciences Instrumentation
|May 12, 2001
PubMed
Summary

This study models the left ventricle using electrical circuits to estimate myocardial visco-elastic properties. A parallel resistor-capacitor model better predicts left ventricular pressure, offering a potential new diagnostic tool for cardiac disorders.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Neurocardiology: translational advancements and potential.

The Journal of physiology·2024
Same author

Targeting protein tyrosine phosphatase σ after myocardial infarction restores cardiac sympathetic innervation and prevents arrhythmias.

Nature communications·2015
Same author

In vivo fluorescence reflectance imaging of protease activity in a mouse model of post-traumatic osteoarthritis.

Osteoarthritis and cartilage·2014
Same author

Flow dynamics of a novel counterpulsation device characterized by CFD and PIV modeling.

Medical engineering & physics·2011
Same author

Ia-like alloantigens in the chicken: Serologic characterization an ontogeny of cellular expression.

Immunogenetics·2011
Same author

Hemodynamic and left ventricular pressure-volume responses to counterpulsation in mock circulation and acute large animal models.

Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference·2007

Area of Science:

  • Biomedical Engineering
  • Cardiovascular Physiology
  • Electrical Engineering

Background:

  • Traditional cardiac performance metrics include blood pressure and cardiac output.
  • Myocardial visco-elastic properties represent novel cardiac source parameters for assessing heart health.

Purpose of the Study:

  • To develop electrical circuit models of the left ventricle.
  • To utilize these models for estimating cardiac source parameters, specifically myocardial visco-elastic properties.

Main Methods:

  • Two electrical models were developed: a single resistor (R) model and a parallel resistor-capacitor (R-C) model.
  • Differential equations governing these models were derived.
  • A minimization procedure adjusted R and C values to match experimental left ventricular pressure data.

Related Experiment Videos

Main Results:

  • Preliminary results show the parallel R-C model provides a superior fit between experimental and calculated left ventricular pressures.
  • This suggests the parallel R-C configuration better represents myocardial visco-elastic properties.

Conclusions:

  • Electrical circuit modeling of the left ventricle is a viable approach for estimating cardiac source parameters.
  • The parallel R-C model shows promise for improved diagnostic capabilities in cardiology.
  • Further research may lead to a new clinical tool for identifying cardiac disorder origins.