Related Experiment Video

Updated: Aug 2, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
12:18

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)

Published on: February 9, 2011

Clinical and microbiological characteristics of 28 patients with Staphylococcus schleiferi infection

J L Hernández1, J Calvo, R Sota

  • 1Department of Internal Medicine, Hospital Universitario Marqués de Valdecilla, University of Cantabria, Santander, Spain. joselhh@teleline.es

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
|May 12, 2001
PubMed

Insights

Staphylococcus schleiferi infections are often associated with wound infections, particularly in immunocompromised men. This study emphasizes the need for accurate laboratory identification, as this bacteria should be considered pathogenic.

Area of Science:

  • Clinical Microbiology
  • Infectious Diseases
  • Bacteriology

Background:

  • Staphylococcus schleiferi is a species of coagulase-negative staphylococci.
  • Coagulase-negative staphylococci are increasingly recognized as human pathogens.
  • Limited data exist on the clinical and microbiological features of S. schleiferi infections.

Purpose of the Study:

  • To analyze the clinical and microbiological characteristics of patients infected with Staphylococcus schleiferi.
  • To determine the spectrum of infections caused by S. schleiferi.
  • To assess the clinical significance and pathogenicity of S. schleiferi.

Main Methods:

  • Retrospective analysis of clinical data and microbiological isolates.
  • Identification of Staphylococcus schleiferi from patient samples.
  • Review of patient demographics, clinical presentation, and outcomes.

Main Results:

  • Seventy-one S. schleiferi isolates were recovered from 36 patients.
  • Infections were more common in men (89.3%) and often occurred in immunocompromised individuals (malignant neoplasms).
  • Wound infections, including surgical-site infections, were most frequent, but unusual infections were also observed; infection-related mortality was low.

Conclusions:

  • Staphylococcus schleiferi is a pathogen associated with various human infections.
  • Accurate identification in clinical microbiology laboratories is crucial.
  • Isolates of S. schleiferi should be considered pathogenic unless proven otherwise.

More Related Videos

Conjunctival Commensal Isolation and Identification in Mice07:52

Conjunctival Commensal Isolation and Identification in Mice

Published on: May 1, 2021

Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients05:26

Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients

Published on: March 1, 2024

Related Concept Videos

Sputum Studies I: Gram Stain, cytology, and Acid-fast smear and culture01:26

Sputum Studies I: Gram Stain, cytology, and Acid-fast smear and culture

Sputum studies are a critical part of diagnosing and treating numerous respiratory conditions. These studies involve obtaining sputum samples for analysis to identify pathogenic organisms and assess the presence of abnormal cells indicative of malignant conditions. This lesson will delve into three fundamental sputum studies: Gram Stain, Cytology, and Acid-fast Smear and Culture.
Gram Stain
The Gram Stain is an integral part of sputum studies. It involves the staining of sputum, which permits...
Sputum Studies II: Culture and Sensitivity01:20

Sputum Studies II: Culture and Sensitivity

Description
Sputum culture and sensitivity is a medical procedure used to diagnose bacterial infections in the respiratory tract and select the most appropriate antibiotics for treatment. This process involves analyzing sputum samples of thick and opaque secretions produced in the lungs and airways. These samples are collected from patients and then sent to the laboratory for analysis.
The test can identify various pathogens responsible for respiratory infections, including Streptococcus,...
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
Clinical Significance of Antibiotic Resistance01:25

Clinical Significance of Antibiotic Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...