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Metabotropic glutamate receptors: structure and new subtype-selective ligands
R Pellicciari1, G Costantino, M Marinozzi
1Dipartimento di Chimica e Tecnologia del Farmaco, Perugia, Italy. rp@unipg.it
Farmaco (Societa Chimica Italiana : 1989)
|May 12, 2001
Abstract:
Metabotropic glutamate receptors (mGluRs) constitute an attractive target for the development of potential neuroprotective agents. Recent advances in the elucidation of the peculiar molecular architecture of mGluRs and in the design and synthesis of subtype selective ligands are discussed.